At E20, the IHC staining intensity of Hspa4l (Figures 5C,D) and Mapk10 (Figures 5E,F) was decreased in embryos with IUGR compared to age-matched controls, while the intensity of Creb3l3 staining increased in IUGR foetuses (Figures 5G,H). Here, CREB3L3 is linked to fetal growth restriction.