Liang et al. found that oxymatrine regulated expression of epithelial-mesenchymal transition (EMT) markers such as E-cadherin, Snail and N-cadherin in colon cancer; expression of p65, a key protein in the NF-κB pathway was lowered at the same time (Liang and Huang, 2016). Here, NFKB1 is linked to malignant colon neoplasm.