In addition, Astragalus saponins reportedly can induce stagnation of cell cycle of G2/M phase in gastric cancer cells and promote the down-regulation of the angiogenic protein vascular endothelial growth factor (VEGF) and metastatic proteins metalloproteinase (MMP), thus inhibiting tumor cell growth (Auyeung et al., 2012). The gene discussed is VEGFA; the disease is neoplasm.