RBPJ and ischemia: Because the deletion of Rbp-J, a key component of Notch signaling, has been reported to promote neural regeneration in MCAO-induced ischemia (Magnusson et al., 2014), we also investigated the changes of the transcription factors in the striatum of astrocyte-specific Rbp-J knockout (KO) mice in order to provide more insight into this process.