In addition to risperidone, which has high affinity to D2R, two other ADHD drugs, atomoxetine and methylphenidate, which act as inhibitors of norepinephrine transporter (NET) and DAT, are able to alleviate ASD-like phenotypes, abnormal catecholamine release, and aberrant dendritic spines in the prefrontal cortex of VPA-treated rats (Choi et al., 2014; Hara et al., 2016). The gene discussed is SLC6A3; the disease is attention deficit-hyperactivity disorder.