ELAVL1 and neurodegenerative disease: Changes in RBPs have been associated with various neurodegenerative diseases (Pascale and Govoni, 2012; De Conti et al., 2017); in particular, the RBP HuR/ELAVL1 regulates the expression of hundreds of genes, including stress response proteins (such as SOD1, p53, Hsp70) (Mazan-Mamczarz et al., 2003; Amadio et al., 2008; Milani et al., 2013) and pro- and anti-inflammatory factors (Nabors et al., 2001), playing a key role in cell survival/apoptosis under stress conditions (Lebedeva et al., 2011).