However, in PCOS subjects, other than BMI, variables related to glucose homeostasis and IR (e.g., FINS, HbA1c, HOMA-IR, OGTT-60 min insulin, OGTT-120 min insulin, and IAUC), as well as TC and liver enzymes (ALT, γ-GGT), were all significantly higher in the overweight/obese subgroup than the normal-weight subgroup (P < 0.05 or P < 0.01). This evidence concerns the gene INS and polycystic ovary syndrome.