Previously, we found that the expression of Hsp90-beta was higher in lung cancer NCI-A549 and NCI-H446 cells than in human bronchial epithelial cells (16-HBE) and increased Hsp90-beta correlated with postoperative survival time and lymph node metastasis of lung cancer patients [11]. The gene discussed is HSP90AB1; the disease is metastatic malignant neoplasm in the lymph nodes.