Some researchers have concluded that early post-operative hypoalbuminemia is associated with the pre-operative serum albumin level, age, and extent of surgery [12], while other studies have shown that post-operative hypoalbuminemia may lead to unfavorable short-term prognoses, such as acute kidney injury [13, 14], unbalanced substance metabolism [15–17], and surgical site infections [18, 19]. The gene discussed is ALB; the disease is Hypoalbuminemia.