Interestingly, whilst gp350-specific T cells were shown to be more efficient than CD19- PBMCs at controlling infected B cells during the early phase of infection (see Fig 3), the CD19- PBMCs of several donors were considerably more adept at restricting B-cell outgrowth than gp350-specific T cells over the longer 15 day period (Fig 4B). This evidence concerns the gene CD19 and infection.