ROR2 and Robinow syndrome: Further, WNT5A and ROR2 are highly expressed in the facial primordia, limb buds, and vertebrae of mice, all areas of the body that are affected in Robinow syndrome patients and bulldogs; additionally, Wnt5a and Ror2 knockout mice exhibit Robinow-like features, including truncated limbs and broad, flat faces [44, 46].