CD4 and HIV-1 infection: To target genes mediating the IFN inhibition of HIV-1, we curated a list of potential ISGs from existing microarray and RNA-seq datasets from cell types relevant to HIV-1 infection, including PBMCs, primary CD4+ T cells, monocyte-derived macrophages (MDMs), monocytes and the THP-1 monocytic cell line (Figure 1—figure supplement 1A and Figure 1—source data 1).