Ligand binding and activated PPARα heterodimerizes with RXRs (Retinoid X receptors) lead to binding peroxisome-proliferator response element (PPRE: AGGTCA N AGGTCA, N is any nucleic acid) that regulates the target gene expression, which is involved in atherosclerosis, diabetes, obesity, inflammation, and cancer [1–7]. Here, PPARA is linked to cancer.