PTPRN and Cowden disease: However, a study comparing the ileal transcriptome in pediatric Crohn's disease (CD) with and without deep ulceration, and with or without ileal involvement (SRP042228) (46), revealed an increased significant expression for Iμ, Iδ, and Iα2 in patients with deep ulcerated CD, regardless the presence of macroscopic or microscopic inflammation (Figure 9 and Table S3).