Despite previous findings indicating that ZNF750 is frequently mutated in head and neck squamous cell carcinoma (HNSC)17,18 and esophageal carcinoma (ESCA)19, ZNF750 was not mutated in the majority of HNSC patients in the cBioPortal dataset20,21 (Figure S1A, B). Here, ZNF750 is linked to head and neck squamous cell carcinoma.