These age-related genes also included several known neurodevelopmental genetic risk loci implicated in ASD (LRP1, RNF135, YWHAE), schizophrenia (TEKT4, LRP1, DNAH1, BRSK1, INTS1, ZC3H10, METTL14), and developmental delay (SCYL1, PIGQ, OBSL1, SMARCB1, CEP135, SPG11, TAF1, TAT, FAM126A, RAD21). The gene discussed is YWHAE; the disease is Global developmental delay.