Several significant age-related proteins mapped to known neurodevelopmental genetic risk loci, including genetic loci implicated in autism spectrum disorder (ASD) (ANK2, YWHAE, L1CAM, FABP5, NRCAM), intellectual disability (L1CAM, PLP1, PSAP, QDPR), and schizophrenia (NCAN, ALCAM, GNAO1, PSAP, NFASC). This evidence concerns the gene NCAN and autism spectrum disorder.