Cirrhotic ascites contains several procoagulants, including but not limited to pre-activated Factor X (Xa) and tissue factor.46 Tissue factor is also abundant in malignant pleural effusions from lung adenocarcinoma patients.47 Therefore, it is plausible that several procoagulants are present in all ascites, regardless of disease origin, and have the potential to activate platelets and thrombosis. This evidence concerns the gene TNXA and lung adenocarcinoma.