Chu et al.77 successfully generated SLAMF7-targeted CAR NK cells that displayed MM cytolytic activity in vitro and ex vivo, as well as efficient suppression of tumour growth in an aggressive orthotopic MM xenograft mouse model.77 A CAR NK cell approach to target CD138 on MM cells was used by Jiang et al.78 who generated NK cells carrying a CAR consisting of an anti-CD138 scFv and CD3ζ. The gene discussed is SDC1; the disease is neoplasm.