Based on these results, we demonstrated by ddPCR that CN changes of PTEN, PDCD4, LKB1 and P70S6K occur also in SS patients used for phospho-array validation (Fig. 2c) and TORC1 activation signaling in vitro (Fig. 3b) as showed in Fig. 4c. The gene discussed is CRTC1; the disease is synovial sarcoma.