The expression level of NR2C2-uORF was measured by Western blot as displayed in Fig. 4b, uORF expression was impaired in human glioma tissues compared with that in NBTs (P < 0.05), which was negatively correlated with the pathological grade of glioma tissues, and the expression level of uORF in NHA was higher than that in glioma cells (P < 0.05). Here, NR2C2 is linked to central nervous system cancer.