We and others have found elevated AURKA levels to be causally linked to loss of primary cilia (Dere et al., 2015; Hasanov et al., 2017; Lolkema et al., 2008; Thoma et al., 2007) in the setting of VHL deficiency. The gene discussed is VHL; the disease is hyperinsulinemic hypoglycemia, familial, 4.