Some anti-cancer drugs (e.g. mitomycin C and 3-hydroxy-5-aziridinyl-1-methyl-2 (1H-indole-4,7-dione)prop-β-en-α-ol or EO9) are reductively activated by NQO1, a fact which means that their activity will be higher in cancer cells which over-express the enzyme [49–52]. This evidence concerns the gene NQO1 and cancer.