The GLP-1 receptor activation alleviates the chronic inflammation response and mitochondrial stress induced by status epilepticus in the lithium-pilocarpine animal model [54], and also has neuroprotective action modifying the microglia phenotype, increasing microglia complexity (enlarged Feret’s diameter), and improving the number of cell junctions and processes in mice [58]. The gene discussed is GLP1R; the disease is status epilepticus.