MTOR and acute respiratory distress syndrome: Considering the complex network regulating autophagy (both mTOR-dependent and mTOR-independent) and apoptosis [44], it is important to follow up on this study to further dissecting the signaling cascades mediating BML-111-activated autophagy and inhibited apoptosis, which will reveal potential targets that could shift the balance of AMs from ALI-induced apoptosis to autophagy.