LCAT and coronary artery disorder: In support of these reported findings, a negative correlation between the plaque volume assessed by intravascular ultrasonography and the LCAT mass concentration has been documented in coronary artery disease patients in recent years, and the authors have suggested that LACT activity is up-regulated with a consequent facilitation of RCT, leading to a reduction in coronary artery plaques in patients with coronary artery disease [23].