Conversely, significantly increased transcriptional expression for cathepsin D precursor (NP_990,508) was observed for the 5 and 10 mg/L TNT doses in the ad libitum feeding group, the 5, 10 and 20 mg/L doses in the restricted diet feeding group, and in the 10 and 20 mg/L TNT doses for non-infected and malaria infected lizards from Exposure 3, respectively (Additional file 1: Table S6). The gene discussed is CTSD; the disease is malaria.