When assessing the impact of IL-17 on BC cell lines (Luminal A MCF-7 and T47D, triple negative MDA-MB435 and MDA-MB231), they observed that metalloproteinase (MMP)-dependent invasion of matrigel was increased in MDA-435 and MDA-MB231, but not on the other cell lines when supplemented with IL-17 [85]. This evidence concerns the gene IL17A and breast cancer.