MMP2 and Familial prostate cancer: At the same time, by up-regulating the expression of miR29b, MBP-1 inhibits the synthesis of collagen and MMP-2 (Matrix Metalloproteinase-2) proteins, which weakens the invasive ability of one prostate cancer cell line, PC13 cells, but suppresses the growth of two other prostate cancer cell lines, DU145 and PC3 cells [34].