Additionally, the apoptosis induced by etoposide, doxorubicin, and cisplatin which are currently used in cancer therapy can be enhanced by c-Myc overexpression in NIH3T3 mouse fibroblasts, TGR-1, HO15.19, and HOmyc3 Rat1 cell lines [70] Therefore, it is worth studying whether these drugs can target MBP-1. This evidence concerns the gene ENO1 and cancer.