NR3C1 and infection: In the other study [41], however, dexamethasone at 10–1000 nM, significantly induced the growth of GR-positive human bladder cancer lines, TCCSUP, and UMUC3, compared with mock treatment, but not that of their GR knockdown sublines derived following an infection with the GR-short hairpin RNA (shRNA) virus, and the stimulatory effects of dexamethasone on cell proliferation were blocked by RU486 which functions as an GR antagonist.