In addition, ERα (p = 0.041; Figure 1a) or ERβ (p = 0.034; Figure 1b) expression in non-muscle-invasive bladder tumors with moderate (2+) to strong (3+) GR expression (n = 55) was associated with a significantly lower or higher risk, respectively, of disease recurrence (Ide et al., unpublished data; immunostaining was performed previously in a set of tissue microarray [24,61]). This evidence concerns the gene ESR1 and urinary bladder neoplasm.