However, further research on TOMM40’s risk for AD was inconclusive, with some studies showing an association with AD in the absence of APOE-4 [17]; and some reports indicating no correlation between TOMM40 poly-T repeat length and age at dementia onset [18,19]; and still others showing that increasing length was associated with a lower risk of AD [20]. The gene discussed is APOE; the disease is Alzheimer disease.