VEGFA and myocardial infarction: In fact, previous works reported that macrophage release of VEGF and TGF‐β is critical to preserve cardiac contraction and healing after myocardial infarction.41 Nonetheless, according to a recent study by de Couto et al., reporting that EVs secreted by cardiosphere‐derived cells exert protective effects against I/R, we provide evidence that EVCT are able to protect cardiomyocytes from I/R‐induced oxidative stress.