PTPN2 and neoplasm: Dividing tumours by their Nottingham grade (NHG), a trend was found where low PTPN2 expression indicated a higher risk for distant recurrence in NHG 1 tumours (HR = 0.41, 95% CI0.12–1.42, P = 0.16) compared with NHG 2–3 tumours (HR = 1.34, 95% CI 0.83–2.15, P = 0.23).