SIRT5 and infection: Two days post-infection, the proportions of bacteremic mice (6/10 vs. 5/10) and blood S. pneumoniae loads (SIRT5+/+ vs. SIRT5−/−: 4.1 ± 2.2 × 103 CFU/ml vs. 4.8 ± 3.6 × 103 CFU/ml; mean ± SEM; P = 0.9) were equivalent in the two groups.