EGFR and non-small cell lung carcinoma: In 40–80% of NSCLCs, the epidermal growth factor receptor (EGFR) has been found to be overexpressed, which is believed to contribute to the NSCLC cell proliferation, differentiation, and survival (Ennis et al., 1991; Salomon et al., 1995; Jutten and Rouschop, 2014).