ABCC10 and non-small cell lung carcinoma: To study the influence of ABCC10 on gefitinib sensitivity in NSCLC cells, we modulated the expression level of ABCC10 either by overexpression in gefitinib-sensitive NSCLC cells, or knockdown in gefitinib-resistant NSCLC cells (Figure 4), then observed the cytotoxic effect of gefitinib.