CNTNAP2 and schizophrenia: It has also been reported that mutations in human CNTNAP2 gene, which encodes a contactin-2 binding protein, is associated with seizures, mental retardation, schizophrenia and autism spectrum disorder (Strauss et al., 2006; Alarcon et al., 2008; Arking et al., 2008; Bakkaloglu et al., 2008; Friedman et al., 2008).