To determine whether depletion of either GSK3α/β or KRas affects MiaPaCa2 and A549 tumor growth in mice, we transfected MiaPaCa2 and A549 cells with non-targeting (NT), KRas, or GSK3α/β siRNA for 48 h and then subcutaneously implanted equal numbers of harvested cells on right (MiaPaCa2) and left (A549) flanks. This evidence concerns the gene KRAS and neoplasm.