In addition, synergistic effects obtained by combining anti-CD73 antibody with NKG2D.CAR-NK-92 cells showed a remarkable and significantly higher delay in tumor growth compared to NKG2D.CAR-NK-92 cells alone (mean tumor volume: 611.5 mm3 vs 1039 mm3, *P < 0.05) (Fig. 6b). This evidence concerns the gene KLRK1 and neoplasm.