We identified 2 novel in-frame fusion genes, EP300-BCORL1 (exon 31-exon 4) in one grade III tumor (EP3) and FOXO1-STK24 (exon 1-exon 3) in one grade II tumor (EP57) (Fig. 1, Additional file 6 Figure S1 and Additional file 9 Figure S4). The gene discussed is EP300; the disease is neoplasm.