Of the 2 tumors carrying BCOR/BCORL1 alterations, EP116 with a verified BCOR tandem duplication was classified as “CNS high grade neuroepithelial tumor with BCOR alteration” (score = 0.99), whereas EP3 with the EP300-BCORL1 fusion with no match, was classified as “CNS high grade neuroepithelial tumor with BCOR alteration” with a low score (0.44). This evidence concerns the gene BCORL1 and neuroepithelial neoplasm.