With simple data analysis, SNP genotype differences in MAP1LC3B (rs7865 and rs9903) in the anthracyclines subgroup, ATM (rs1003623) and ATG13 (rs10838611) in the CTX subgroup, MAP1LC3B (rs7865) in the PTX subgroup, and MAP1LC3A (rs6088521) in the DTX subgroup demonstrated potential associations with cardiac toxicity. The gene discussed is ATG13; the disease is cerebrotendinous xanthomatosis.