A significant high expression of NKp30 and NKp46 was detected in VHL-MUT-RCC as compared to VHL-WT-RCC samples (p = 0.04 and p = 0.017, respectively, Fig. 3C and D) and NKp44 and DNAM-1 were slightly overexpressed in VHL-MUT compared to VHL-WT patients. This evidence concerns the gene NCR3 and renal cell carcinoma.