LEP and chronic obstructive pulmonary disease: Considering that the BMI showed no difference between the groups of COPD, it might evidence that BMI in not determinant to the develop of systemic inflammation in COPD-BS; thus, the role of ghrelin, insulin, leptin, PAI-1, and visfatin in women exposed to BS seems take an important physiopathogenic role in the develop of systemic inflammation in COPD in this women.