SOX30 and AIDS dementia complex: In our present study, Kaplan-Meier and Cox regression analyses revealed that SOX30 expression was significantly correlated with ADC patient’s survival, especially with OS of the ADC patients at stage I. The elevated SOX30 expression inhibited tumor-metastasis and represented as a favorable prognostic biomarker of the ADC patients at stage I. These data suggest that SOX30 serves as a new favorable early-stage prognostic candidate for ADC patients, which can be used to accurately predict clinical outcomes of ADC patients.