The percentage of negative CTNNB1 samples in SOX30 high-expression group (60.00%, 18/30) was much higher than in SOX30 low-expression group (22.64%, 12/53) of ADC patients (p = 0.001) (Additional file 1: Table S3), however there was no difference of the percentage of negative CTNNB1 between SOX30 high- and low-expression groups of SCC patients (p = 0.910) (Additional file 1: Table S3). This evidence concerns the gene SOX30 and AIDS dementia complex.