SOX30 and AIDS dementia complex: To investigate the role of SOX30 on cancer cell metastasis, we generated gain-of-function cell models in ADC cell lines (A549 and SPC-A-1) and SCC cell lines (H520 and H2170) by transfecting SOX30 or empty vector plasmids (Fig. 2a), and determined cell migration and invasion by transwell assays.