To determine the possible mechanism for different roles of SOX30 on anti- metastasis in ADC and SCC, we generated global SOX30-regulated networks for potential targets using RNA array profiles in stably transfected ADC (A549) and SCC (H520) cell lines, and identified an important gene network of Wnt/CTNNB1-signaling only in ADC cell line (Fig. 3c). The gene discussed is SOX30; the disease is AIDS dementia complex.