ALX40-4C (N-α-acetyl-nona-d-arginine amide acetate), which selectively blocks the interaction of SDF-1 with CXCR4, inhibits breast carcinoma cell invasion without decreasing cell viability [136], suggesting a distinct contribution of CXCR4 to the invasion but not to the survival of breast cancer cells. This evidence concerns the gene CXCR4 and breast cancer.