These include folliculin (FLCN; chromophobe RCC/oncocytoma in Birt–Hogg–Dubé syndrome), papillary type 1 RCC (MET), fumarate hydratase (FH; papillary type 2 RCC in hereditary leiomyomatosis and renal cell cancer syndrome), SDHB/SDHD/SDHC/SDHA (succinate dehydrogenase subunit-related RCC), chromosome 3 translocations-associated clear cell RCC, papillary RCC (PTEN), and BAP1 (clear cell RCC) [18]. This evidence concerns the gene FH and hereditary leiomyomatosis and renal cell cancer.