In a focal ischemia model based on occlusion of the cerebral artery, BAI2 expression decreases in the ischemic cerebral cortex after ischemia induction, and the expression level of BAI2 inversely correlates with that of a vascular endothelial growth factor (VEGF), which is a key mediator of angiogenesis [13]. This evidence concerns the gene VEGFA and ischemia.