ZFHX3 and cancer: Closer examination of genes that were dysregulated in CTCF-altered cancers showed expression of the CTCF paralog CTCFL was decreased (p = 0.0167; Supplementary Figure S3D), the exemplar CTCF-regulated gene H19 was decreased (p = 0.0087; Supplementary Figure S3E), whilst no change was observed in ZFHX3 expression which is located adjacent to CTCF on chromosome 16q22 (Supplementary Figure S3F).