SAAL1 and rheumatoid arthritis: In our previous study, we identified synoviocyte proliferation-associated in collagen-induced arthritis (CIA) 1/serum amyloid A-like 1 (SPACIA1/SAAL1) as an overexpressed gene in the joint tissue of mice with CIA and indicated that the gene was associated with abnormal synovial proliferation in human RA [7].