SIRT1 and gestational diabetes: Interestingly, a recent study by Rezaei Farimani et al. [52] reported that resveratrol increases SNAP23 gene expression in diabetic animals; it is hence theoretically possible that the increased leukocyte SNAP23 expression in the GDM/SIRT1(↑) group observed in our study could be an adaptive response to SIRT1 overexpression in diabetic pregnancies.