The gene expression analysis revealed that of the six selected genes, four demonstrated a significantly different expression between the GDM/SIRT1(↑) and the NGT group (p < 0.05): ACLY (FC = 0.63) displayed a significantly lower expression, while G6PD (FC = 1.52), IL6 (FC = 2.29), and SNAP23 (FC = 6.55) demonstrated a significantly increased expression. The gene discussed is ACLY; the disease is gestational diabetes.