SIRT1 and gestational diabetes: The univariate correlation analyses revealed significant positive associations between leukocyte SIRT1 gene expression and plasma glucose measurements at fasting (R = 0.41, p < 0.001) and when following the OGTT (R = 0.32, p = 0.015 and R = 0.76, p < 0.001 for 1-h and 2-h post-load glucose concentrations, respectively), as well as with plasma HbA1c level (R = 0.31, p = 0.010) in the entire study group (NGT+ GDM/SIRT1(↑), n = 71) (Table 2).