As the complex molecular events related with SIRT1 overexpression in leukocytes of GDM patients were unknown, the study also compared the changes in leukocyte-induced expression of diabetes-related genes taking place in hyperglycemic GDM/SIRT1(↑) women with those in the NGT controls using RT-qPCR array technology. This evidence concerns the gene SIRT1 and diabetes mellitus.