PTGS2 and neuroblastoma: Chen et al. [6] reported that 11-dehydrosinulariolide suppressed 6-hydroxydopamine-induced cytotoxicity and apoptosis in a human neuroblastoma cell line, SH-SY5Y, and reduced the expression of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) proteins in lipopolysaccharide-stimulated macrophage cells.