CRP and neoplasm: These factors include lactate dehydrogenase (LDH) levels, C-reactive protein (CRP) levels, the neutrophil-to-lymphocyte ratio (NLR) and the platelet-lymphocyte ratio (PLR), and the tumor biomarkers in CRC, carcinoembryonic antigen (CEA) and carbohydrate antigen 19–9 (CA 19–9), also rise under inflammatory conditions [11, 12].