Mutations in BRAF, NRAS or NF1 in MM are less prevalent than in CM, with loss of PTEN (4–25% of samples 3, 54) mutation or amplification of KIT (7–25% of MM samples 3, 54, 132) and CCND1 or CDK4104 being more common (Table 1). This evidence concerns the gene NF1 and Miyoshi myopathy.